A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more than 253,000 individual cells and identifying previously hidden ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Using single-cell sequencing and spatial tools, researchers have created the most comprehensive map of the maternal–fetal interface yet.

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, regional differences, and potential biomarkers of brain aging. More than 57 ...

Scientists mapped the maternal–fetal interface revealing new cell types, genetic links, and mechanisms behind pregnancy complications.

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...