When proteins are made in a cell, they start out as strings of amino acids, which have to be folded into the correct, three-dimensional shape so they will function properly. Misfolded proteins can ...

Daniel Ojeda Juarez, a postdoctoral researcher at UC San Diego, explores the link between protein aggregation and cognitive ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD) from cervids—deer, elk ...

Scientists at Northwestern University and University of California, Santa Barbara have created the first synthetic fragment of tau protein that acts like a prion. The “mini prion” folds and stacks ...

AMES, Iowa – Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion ...

In the field of COVID-19 research, attention has turned to a critical aspect: the prion region on the surface spike proteins of the virus and its implications, especially in the context of mRNA ...

Transmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases that include bovine spongiform encephalopathy (BSE), scrapie in sheep, and Creutzfeldt–Jakob disease ...