Why do memories fade in Alzheimer's disease—and can they be restored? University of California, Irvine researchers have ...

Scientists have identified a new factor that may explain why memory declines in Alzheimer’s disease, pointing to a disruption ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...

Recent research has shown that non-invasive brain stimulation (NIBS), transcranial magnetic stimulation (TMS) in particular, can modulate core memory ...

UC Irvine scientists have identified severe dopamine depletion in the entorhinal cortex as a key driver of memory loss in Alzheimer’s disease. In mouse models, restoring dopamine with optogenetics or ...

On average, human memory declines with age. However, there is substantial variation among individuals: some experience a rapid decline, whereas others barely notice a change. With our rapidly aging ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work ...

Context memory formation is a complex process that requires transcription in many subregions of the brain including the dorsal hippocampus and retrosplenial cortex. One critical gene necessary for ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...