Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers. Published online in Science on Oct. 30, the study shows that ...

Schematic model showing how memory is consolidated in the prefrontal cortex and how circuitry through the amygdala shifts as hippocampal engram cells become silent and cortical engrams become active.

Deep in the lungs, resident memory B cells stand guard against influenza reinfection—but whether they remain there may depend ...

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and ...

Immediate-early genes (IEGs), including c-Fos, are integral to the brain's response to stimuli. Initially identified as a proto-oncogene, c-Fos is essential for neural activity, synaptic plasticity, ...

Computational models show that even subtle modifications in the synaptic protein CaMKII completely alter the resulting protein structures. Given how the formation and stability of these structures ...