Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved the first chimeric antigen receptor therapy in 2017, authorizing tisagenlecleucel for treatment ...

Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic ...

In vivo models of human immunity in human tumor-bearing mice are frequently used to study mechanisms of targeted immunotherapies, safety, and efficacy. In a recent webinar Jenny Rowe, PhD, Scientist ...

Creating better, more reliable rodent models of Alzheimer’s disease has been a struggle for researchers. On October 19 in Molecular Neurodegeneration, scientists led by Bart De Strooper at KU Leuven, ...