Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...

Delve into the field of PARP inhibitors, a class that has gained traction in ovarian, breast, and prostate cancers.

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

Targeted DNA editing by CRISPR technology has great potential for applications in biotechnology and gene therapy. However, precise gene editing remains a challenge largely due to insufficient control ...

Scientists are uncovering a deeper layer of DNA biology—where its shape, stiffness, and 3D organization are just as important as its sequence. New tools are mapping how replication starts, how damage ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...

Forbes contributors publish independent expert analyses and insights. I write about biodiversity and the hidden quirks of the natural world. Recent research on bowhead whale DNA repair has led to one ...

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...