Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development in mice. In the new study, published in Nature Communications, a ...

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically female mouse embryos into anatomically male mice. The experiment, published ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...

A study shows that changes in noncoding genes can trigger autoimmune diabetes in infants by affecting hundreds of ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.

Using artificial intelligence, Garvan Institute researchers have found potential cancer drivers hidden in so-called 'junk' regions of DNA, opening up possibilities for a new approach to diagnosis and ...