T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

Researchers found that intestinal tuft cells signal to crypt enterochromaffin cells by releasing acetylcholine, triggering serotonin release and activating a gut-to-brain vagal pathway during type 2 ...

Cancer-fighting T cells do not simply "run out of energy." They are molecularly reprogrammed. For years, mitochondrial ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors that many common medicines target. Subscribe to our newsletter for the latest ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers have discovered how mitochondrial stress drives T cell exhaustion and a potential way to restore their ...

Scientists led by Sergey Troyanovsky, Ph.D., professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process ...

Researchers have established a direct experimental link between inflammatory signals in the intestinal lining and the kind of ...