The power of CRISPR became definitively clear when the first CRISPR-based gene therapy, Casgevy (exa-cel), won regulatory approvals for the treatment of sickle cell disease. But CRISPR’s applications ...
CRISPR-Cas9 technology is used to knock out or modify DNA in research mice to study disease phenotypes and develop new treatments. CRISPR mice and rats are offered by Charles River, which uses genetic ...
Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...
NASA astronaut Nick Hague runs an analysis with the miniPCR hardware for Genes in Space-6 during Expedition 59. This experiment explored how space radiation damages DNA and how cells repair that ...
Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...
Pigs whose DNA makes them resistant to a virus could be the first big consumer product using gene editing. Most pigs in the US are confined to factory farms where they can be afflicted by a nasty ...